• DocumentCode
    1053216
  • Title

    In vivo NMR relaxation studies of tumors

  • Author

    Weisman, Irwin D. ; Bennett, Lawrence H. ; Maxwell, Louis R., Sr.

  • Author_Institution
    Institute for Materials Research, National Bureau of Standards, Gaithersburg, Md.
  • Volume
    9
  • Issue
    3
  • fYear
    1973
  • fDate
    9/1/1973 12:00:00 AM
  • Firstpage
    454
  • Lastpage
    456
  • Abstract
    Pulsed nuclear magnetic resonance has been used to differentiate between normal mouse tail tissue and a malignant transplanted melanoma S91 located on the tail of a live mouse. Measurements of proton spin-lattice and spin-spin relaxation serve to detect and monitor the tumor growth. The mature tumor exhibits a spin-lattice relaxation time T1of \\sim0.7- 0.8 s contrasting with the corresponding normal tail tissue T1of half this value. On the other hand spin-spin relaxation in normal tissue cannot be characterized by a single relaxation time T2. The corresponding relaxation in a mature tumor is found to be closer to a single exponential but still requires at least two superimposed exponential decays.
  • Keywords
    Biomagnetics; Biomedical measurements; Cancerous tissues; Nuclear magnetic resonance; Tumors; Cancer; Coils; In vivo; Malignant tumors; Mice; Monitoring; Neoplasms; Nuclear magnetic resonance; Radio frequency; Tail;
  • fLanguage
    English
  • Journal_Title
    Magnetics, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9464
  • Type

    jour

  • DOI
    10.1109/TMAG.1973.1067678
  • Filename
    1067678
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1053216