Title :
A valved responsive hydrogel microdispensing device with integrated pressure source
Author :
Eddington, David T. ; Beebe, David J.
Author_Institution :
Dept. of Biomed. Eng., Wisconsin Univ., Madison, WI, USA
Abstract :
Stimulus responsive hydrogels provide the actuation pressure required for both valving and dispensing functions in the device presented. The microdispensing device uses an array of responsive hydrogels to deform a flexible membrane above a fluid reservoir chamber. When the microvalve is open, the deformation of the membrane reduces the volume of the reservoir chamber and pushes fluid through the microvalve. When the microvalve is closed, the expanding hydrogel array generates a storable pressure source that will result in fluid dispensing once the microvalve is opened. Experiments determined the pressure generated by this device to be 35 kPa. The device has a stroke volume of 45 μL, and is able to hold the pressure for over 24 h.
Keywords :
microactuators; microfluidics; microvalves; polymer gels; 24 h; 35 kPa; actuation pressure; dispensing functions; fluid reservoir chamber; hydrogel array; hydrogel microdispensing device; integrated pressure source; microfluidic; microvalve; poly-dimethylsiloxane; responsive hydrogels; responsive stimulus; storable pressure source; stroke volume; valving; Actuators; Biomembranes; Chemicals; Drug delivery; Helium; Microfluidics; Micropumps; Microvalves; Protein engineering; Reservoirs; Dispensing device; PDMS; hydrogel; microfluidic; polydimethylsiloxane; pressure source;
Journal_Title :
Microelectromechanical Systems, Journal of
DOI :
10.1109/JMEMS.2004.832190