DocumentCode
1054331
Title
A valved responsive hydrogel microdispensing device with integrated pressure source
Author
Eddington, David T. ; Beebe, David J.
Author_Institution
Dept. of Biomed. Eng., Wisconsin Univ., Madison, WI, USA
Volume
13
Issue
4
fYear
2004
Firstpage
586
Lastpage
593
Abstract
Stimulus responsive hydrogels provide the actuation pressure required for both valving and dispensing functions in the device presented. The microdispensing device uses an array of responsive hydrogels to deform a flexible membrane above a fluid reservoir chamber. When the microvalve is open, the deformation of the membrane reduces the volume of the reservoir chamber and pushes fluid through the microvalve. When the microvalve is closed, the expanding hydrogel array generates a storable pressure source that will result in fluid dispensing once the microvalve is opened. Experiments determined the pressure generated by this device to be 35 kPa. The device has a stroke volume of 45 μL, and is able to hold the pressure for over 24 h.
Keywords
microactuators; microfluidics; microvalves; polymer gels; 24 h; 35 kPa; actuation pressure; dispensing functions; fluid reservoir chamber; hydrogel array; hydrogel microdispensing device; integrated pressure source; microfluidic; microvalve; poly-dimethylsiloxane; responsive hydrogels; responsive stimulus; storable pressure source; stroke volume; valving; Actuators; Biomembranes; Chemicals; Drug delivery; Helium; Microfluidics; Micropumps; Microvalves; Protein engineering; Reservoirs; Dispensing device; PDMS; hydrogel; microfluidic; polydimethylsiloxane; pressure source;
fLanguage
English
Journal_Title
Microelectromechanical Systems, Journal of
Publisher
ieee
ISSN
1057-7157
Type
jour
DOI
10.1109/JMEMS.2004.832190
Filename
1321095
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