Modelling Fibrillation Potentials—Analysis of Time Parameters in the Muscle Intracellular Action Potential

A single fiber action potential (SFAP) can be modelled as the convolution of a biolectrical source and a filter impulse response. In the Dimitrov-Dimitrova (D-D) convolutional model, the first temporal derivative of the intracellular action potential (IAP) is used as the source, and is a time parameter related to the duration of the IAP waveform. This paper is centred on the relation between T_spl and the main spike duration (MSD), defined as the time interval between the first and third phases of the SFAP. We show that T_spl essentially determines the MSD parameter. As experimental data, we used fibrillation potentials (FPs) of two different muscles to study the D-D model. We found that should have a certain statistical variability in order to explain the variability in the MSD of our FPs. In addition, we present a method to estimate the values corresponding to a given SFAP from its measured MSD.