Dynamic Cell and Microparticle Control via Optoelectronic Tweezers

Author

Ohta, Aaron Takami ; Chiou, Pei-Yu ; Han, Tae H. ; Liao, James C. ; Bhardwaj, Urvashi ; McCabe, Edward R B ; Yu, Fuqu ; Sun, Ren ; Wu, Ming C.

Author_Institution

California Univ., Berkeley

Volume

16

Issue

3

fYear

2007

fDate

6/1/2007 12:00:00 AM

Firstpage

491

Lastpage

499

Abstract

This paper reports on cell and microparticle manipulation using optically induced dielectrophoresis. Our novel optoelectronic tweezers (OET) device enables optically controlled trapping, transportation, and sorting via dielectrophoretic forces. By integrating a spatial light modulator and using direct imaging, arbitrary dynamic manipulation patterns are obtained. Here, we demonstrate manipulation functions, including particle collectors, single-particle traps, individually addressable single-particle arrays, light-defined particle channels, and size-based particle sorting. OET-induced particle manipulation velocities are analyzed as a function of the applied voltage, optical pattern linewidth, and single-particle trap dimensions.

Keywords

electrophoresis; optoelectronic devices; particle traps; spatial light modulators; dynamic cell; microparticle control; microparticle manipulation; optical pattern linewidth; optically controlled trapping; optically induced dielectrophoresis; optoelectronic tweezers; particle collectors; single-particle traps; spatial light modulator; Charge carrier processes; Dielectrophoresis; Force control; Manipulator dynamics; Optical control; Optical devices; Optical imaging; Optical modulation; Sorting; Transportation; Dielectrophoresis (DEP); optical tweezers; optically induced DEP; optoelectronic tweezers (OET);

fLanguage

English

Journal_Title

Microelectromechanical Systems, Journal of

Publisher

ieee

ISSN

1057-7157

Type

jour

DOI

10.1109/JMEMS.2007.896717

Filename

4276814