• DocumentCode
    1069832
  • Title

    Estimation of Channelized Hotelling Observer Performance With Known Class Means or Known Difference of Class Means

  • Author

    Wunderlich, Adam ; Noo, Frédéric

  • Author_Institution
    Dept. of Radiol., Univ. of Utah, Salt Lake City, UT, USA
  • Volume
    28
  • Issue
    8
  • fYear
    2009
  • Firstpage
    1198
  • Lastpage
    1207
  • Abstract
    This paper concerns task-based image quality assessment for the task of discriminating between two classes of images. We address the problem of estimating two widely-used detection performance measures, SNR and AUC, from a finite number of images, assuming that the class discrimination is performed with a channelized Hotelling observer. In particular, we investigate the advantage that can be gained when either 1) the means of the signal-absent and signal-present classes are both known, or 2) when the difference of class means is known. For these two scenarios, we propose uniformly minimum variance unbiased estimators of SNR2, derive the corresponding sampling distributions and provide variance expressions. In addition, we demonstrate how the bias and variance for the related AUC estimators may be calculated numerically by using the sampling distributions for the SNR2 estimators. We find that for both SNR2 and AUC, the new estimators have significantly lower bias and mean-square error than the traditional estimator, which assumes that the class means, and their difference, are unknown.
  • Keywords
    biomedical imaging; AUC estimator; SNR2 estimator; channelized hotelling observer performance; class means; task based image quality assessment; Cities and towns; Computed tomography; Humans; Image quality; Lesions; Mathematical model; Performance evaluation; Radiology; Signal to noise ratio; X-ray imaging; AUC; class discrimination; estimation; image quality; receiver operating characteristic (ROC); signal-to-noise ratio (SNR); Algorithms; Area Under Curve; Image Interpretation, Computer-Assisted; ROC Curve; Signal Processing, Computer-Assisted; Statistics, Nonparametric;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/TMI.2009.2012705
  • Filename
    4752740