• DocumentCode
    1075086
  • Title

    Exploring Peripheral Mechanism of Tremor on Neuromusculoskeletal Model: A General Simulation Study

  • Author

    Zhang, Dingguo ; Poignet, Philippe ; Bo, Antônio P L ; Ang, Wei Tech

  • Author_Institution
    Shanghai Jiao Tong Univ., Shanghai, China
  • Volume
    56
  • Issue
    10
  • fYear
    2009
  • Firstpage
    2359
  • Lastpage
    2369
  • Abstract
    This paper provides a general simulation study on tremor based on a modular neuromusculoskeletal model. It focuses on the peripheral mechanism. It is known that the reflex loops in the peripheral nervous system have influences on the tremor. A neuromusculoskeletal model with several reflex loops is developed to explore the dynamics of tremor. The muscle model is derived from a Hill-type muscle model. The reflex loops include the spindle organ, Golgi tendon organ, and Renshaw cell. Their effects are investigated quantitatively in detail. A two-muscle (agonist/antagonist) system with interaction is further studied. Moreover, a model in combination with the central oscillation and peripheral system is developed. Some results are in accordance with the previous research, whereas some new findings are proposed according to the simulation study.
  • Keywords
    biological organs; neuromuscular stimulation; physiological models; Golgi tendon organ; Hill-type muscle model; Renshaw cell; central oscillation; modular neuromusculoskeletal model; peripheral nervous system; spindle organ; tremor; two-muscle system; Frequency; Medical treatment; Multiple sclerosis; Muscles; Nervous system; Oscillators; Parkinson´s disease; Pathogens; Pathology; Tendons; Central oscillator; neuromusculoskeletal modeling; peripheral neural dynamics; reflex loops; tremor; Algorithms; Computer Simulation; Electric Stimulation; Feedback; Humans; Models, Biological; Muscle, Skeletal; Peripheral Nerves; Torque; Tremor; Wrist Joint;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2009.2023979
  • Filename
    5075574