Title :
Low-cost magnetic interdigitated array on a plastic wafer
Author :
Do, Jaephil ; Choi, Jin-Woo ; Ahn, Chong H.
Author_Institution :
Electr. & Comput. Eng. & Comput. Sci. Dept., Univ. of Cincinnati, OH, USA
fDate :
7/1/2004 12:00:00 AM
Abstract :
In this paper, a new magnetic interdigitated array (mIDA) has been designed, fabricated, and characterized for a magnetic bead separator on a plastic substrate, which can provide sampling capability in a low-cost disposable platform for magnetic bead-based biochemical detection systems. A mIDA was patterned and electroplated on a cyclic olefin copolymer (COC) substrate. To construct a magnetic bead sampler, an injection-molded microchannel layer on the COC was bonded over the mIDA using plastic thermal fusion bonding techniques. The microfabricated mIDA was excited using an external microelectromagnet to characterize the magnetic separator. Magnetic beads in a diameter of 2.0-9.0 μm were successfully separated over the mIDA from an aqueous solution with magnetic beads at a flow rate of 3.0-7.0 μl/min.
Keywords :
biosensors; chemical sensors; electromagnets; magnetic separation; micromachining; substrates; 2.0 to 9.0 micron; aqueous solution; biochemical detector; cyclic olefin copolymer substrate; disposable magnetic separator; external microelectromagnet; injection-molded microchannel layer; low-cost disposable platform; low-cost magnetic interdigitated array; magnetic bead sampler; magnetic bead separator; magnetic bead-based biochemical detection; magnetic beads; microfabricated MIDA; plastic substrate; plastic thermal fusion bonding; plastic wafer; sampling capability; Bonding; Electromagnets; Fingers; Magnetic fields; Magnetic flux; Magnetic separation; Microchannel; Micromagnetics; Particle separators; Plastics; Biochemical detector; disposable magnetic separator; mIDA; magnetic bead; magnetic interdigitated array;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2004.828979
