DocumentCode
1080338
Title
Improved Parameterized Complexity of the Maximum Agreement Subtree and Maximum Compatible Tree Problems
Author
Berry, V. ; Nicolas, F.
Author_Institution
Equipe Methodes et Algorithmes pour la Bioinformatique, LIRMM, Montpellier
Volume
3
Issue
3
fYear
2006
Firstpage
289
Lastpage
302
Abstract
Given a set of evolutionary trees on a same set of taxa, the maximum agreement subtree problem (MAST), respectively, maximum compatible tree problem (MCT), consists of finding a largest subset of taxa such that all input trees restricted to these taxa are isomorphic, respectively compatible. These problems have several applications in phylogenetics such as the computation of a consensus of phylogenies obtained from different data sets, the identification of species subjected to horizontal gene transfers and, more recently, the inference of supertrees, e.g., Trees Of Life. We provide two linear time algorithms to check the isomorphism, respectively, compatibility, of a set of trees or otherwise identify a conflict between the trees with respect to the relative location of a small subset of taxa. Then, we use these algorithms as subroutines to solve MAST and MCT on rooted or unrooted trees of unbounded degree. More precisely, we give exact fixed-parameter tractable algorithms, whose running time is uniformly polynomial when the number of taxa on which the trees disagree is bounded. The improves on a known result for MAST and proves fixed-parameter tractability for MCT
Keywords
biology computing; cellular biophysics; evolution (biological); genetics; isomorphism; molecular biophysics; trees (mathematics); evolutionary trees; fixed-parameter tractable algorithms; improved parameterized complexity; isomorphism; linear time algorithms; maximum agreement subtree problem; maximum compatible tree problem; phylogenetics; phylogeny; supertrees; taxa; Bioinformatics; History; Inference algorithms; Maximum likelihood estimation; Packaging; Pattern matching; Phylogeny; Polynomials; Sequences; Systematics; Phylogenetics; algorithms; compatibility; consensus; fixed-parameter tractability.; pattern matching; trees; Algorithms; Biological Evolution; Evolution, Molecular; Genetics, Population; Likelihood Functions; Models, Genetic; Pedigree; Phylogeny; Sequence Analysis, DNA;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2006.39
Filename
1668027
Link To Document