DocumentCode
1086555
Title
Carbon Nanotube Fibers Are Compatible With Mammalian Cells and Neurons
Author
Dubin, Robert A. ; Callegari, Gerardo C. ; Kohn, Joachim ; Neimark, Alexander V.
Author_Institution
State Univ. of New Jersey, Piscataway
Volume
7
Issue
1
fYear
2008
fDate
3/1/2008 12:00:00 AM
Firstpage
11
Lastpage
14
Abstract
We demonstrate the biocompatibility of carbon nanotube fibers (CNFs) fabricated from single-wall carbon nanotubes. Produced by a particle-coagulation spinning process, CNFs are "hair-like" conductive microwires, which uniquely combine properties of porous nanostructured scaffolds, high-area electrodes, and permeable microfluidic conduits. We report that CNFs are nontoxic and support the attachment, spreading, and growth of mammalian cells and the extension of processes from neurons in vitro. Our findings suggest that CNF may be employed for an electrical interfacing of nerve cells and external devices.
Keywords
biomedical materials; carbon fibres; carbon nanotubes; cellular biophysics; electrical conductivity; nanobiotechnology; biocompatibility; carbon nanotube fibers; conductive microwires; electrical conductivity; electrodes; mammalian cells; neurons; nontoxicity; particle-coagulation spinning process; permeable microfluidic conduits; porous nanostructured scaffolds; single-wall carbon nanotubes; Carbon nanotubes; Coagulation; Electrodes; In vitro; Morphology; Nanoporous materials; Neurons; Personal communication networks; Spinning; Biocompatibility; carbon nanotubes; cell adhesion; neurons; Animals; Biocompatible Materials; Cell Adhesion; Cell Survival; Materials Testing; Mice; NIH 3T3 Cells; Nanotubes, Carbon; Neurons; Particle Size;
fLanguage
English
Journal_Title
NanoBioscience, IEEE Transactions on
Publisher
ieee
ISSN
1536-1241
Type
jour
DOI
10.1109/TNB.2008.2000144
Filename
4459719
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