• DocumentCode
    1086555
  • Title

    Carbon Nanotube Fibers Are Compatible With Mammalian Cells and Neurons

  • Author

    Dubin, Robert A. ; Callegari, Gerardo C. ; Kohn, Joachim ; Neimark, Alexander V.

  • Author_Institution
    State Univ. of New Jersey, Piscataway
  • Volume
    7
  • Issue
    1
  • fYear
    2008
  • fDate
    3/1/2008 12:00:00 AM
  • Firstpage
    11
  • Lastpage
    14
  • Abstract
    We demonstrate the biocompatibility of carbon nanotube fibers (CNFs) fabricated from single-wall carbon nanotubes. Produced by a particle-coagulation spinning process, CNFs are "hair-like" conductive microwires, which uniquely combine properties of porous nanostructured scaffolds, high-area electrodes, and permeable microfluidic conduits. We report that CNFs are nontoxic and support the attachment, spreading, and growth of mammalian cells and the extension of processes from neurons in vitro. Our findings suggest that CNF may be employed for an electrical interfacing of nerve cells and external devices.
  • Keywords
    biomedical materials; carbon fibres; carbon nanotubes; cellular biophysics; electrical conductivity; nanobiotechnology; biocompatibility; carbon nanotube fibers; conductive microwires; electrical conductivity; electrodes; mammalian cells; neurons; nontoxicity; particle-coagulation spinning process; permeable microfluidic conduits; porous nanostructured scaffolds; single-wall carbon nanotubes; Carbon nanotubes; Coagulation; Electrodes; In vitro; Morphology; Nanoporous materials; Neurons; Personal communication networks; Spinning; Biocompatibility; carbon nanotubes; cell adhesion; neurons; Animals; Biocompatible Materials; Cell Adhesion; Cell Survival; Materials Testing; Mice; NIH 3T3 Cells; Nanotubes, Carbon; Neurons; Particle Size;
  • fLanguage
    English
  • Journal_Title
    NanoBioscience, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    1536-1241
  • Type

    jour

  • DOI
    10.1109/TNB.2008.2000144
  • Filename
    4459719