Title :
Real-time Microwave Imaging of Differential Temperature for Thermal Therapy Monitoring
Author :
Haynes, Mark ; Stang, John ; Moghaddam, Mahta
Author_Institution :
Dept. of Electr. Eng.-Electrophys., Univ. of Southern California, Los Angeles, CA, USA
Abstract :
A microwave imaging system for real-time 3-D imaging of differential temperature has been developed for the monitoring and feedback of thermal therapy systems. Design parameters are constrained by features of a prototype-focused microwave thermal therapy system for the breast, operating at 915 MHz. Real-time imaging is accomplished with a precomputed linear inverse scattering solution combined with continuous vector network analyzer (VNA) measurements of a 36-antenna, HFSS-modeled, cylindrical cavity. Volumetric images of differential change of dielectric constant due to temperature are formed with a refresh rate as fast as 1 frame/s and 1 °C resolution. Procedures for data segmentation and postprocessed S-parameter error-correction are developed. Antenna pair VNA calibration is accelerated by using the cavity as the unknown thru standard. The device is tested on water targets and a simple breast phantom. Differentially heated targets are successfully imaged in cluttered environments. The rate of change of scattering contrast magnitude correlates 1:1 with target temperature.
Keywords :
antennas; biological organs; biothermics; calibration; image segmentation; medical image processing; patient monitoring; patient treatment; permittivity; phantoms; HFSS-modeled cavity; VNA measurements; antenna pair VNA calibration; cluttered environments; cylindrical cavity; data segmentation; dielectric constant; differential temperature; differentially heated targets; postprocessed S-parameter error-correction; precomputed linear inverse scattering solution; prototype-focused microwave thermal therapy system; real-time 3-D imaging; real-time microwave imaging; simple breast phantom; thermal therapy monitoring; thermal therapy systems; vector network analyzer; volumetric images; Biomedical measurement; Calibration; Cavity resonators; Microwave imaging; Scattering parameters; Temperature measurement; Biomedical imaging; Born approximation (BA); biomedical monitoring; calibration; distorted Born approximation (DBA); inverse scattering; microwave breast hyperthermia; microwave breast imaging; microwave imaging; temperature measurement; vector network analyzer (VNA);
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2014.2307072