DocumentCode
1092429
Title
Computational approach to systems biology: from fraction to integration and beyond
Author
Dhar, Pawan K. ; Zhu, Hao ; Mishra, Santosh K.
Author_Institution
Syst. Biol. Group, Bioinformatics Inst., Singapore
Volume
3
Issue
3
fYear
2004
Firstpage
144
Lastpage
152
Abstract
Systems biology is an approach to understanding the workings of whole biological systems. The various methods used for systems analyses range from experimental to computational. In this paper, we describe basic concepts of systems biology, modeling challenges that arise from the massively parallel interaction among components in biological systems, and what lies beyond integration of modular knowledge.
Keywords
biology computing; cellular automata; physiological models; cellular automata; computational approach; fraction; integration; modeling; modular knowledge; systems analysis; systems biology; whole biological systems; Automata; Bioinformatics; Biological system modeling; Biological systems; Biology computing; Data engineering; Equations; Mathematical model; Systems biology; Throughput; Animals; Cell Physiology; Computational Biology; Computer Simulation; Gene Expression Regulation; Humans; Models, Biological; Signal Transduction; Systems Biology; Systems Integration;
fLanguage
English
Journal_Title
NanoBioscience, IEEE Transactions on
Publisher
ieee
ISSN
1536-1241
Type
jour
DOI
10.1109/TNB.2004.833699
Filename
1331339
Link To Document