Title :
Noise Correction on Rician Distributed Data for Fibre Orientation Estimators
Author :
Clarke, Rafael Alonso ; Scifo, Paola ; Rizzo, Giovanna ; Dell´Acqua, Fabio ; Scotti, Giuseppe ; Fazio, Ferruccio
Author_Institution :
Dept. of Nucl. Med., San Raffaele Sci. Inst., Milan
Abstract :
New complex tissue microstructure estimators have been presented recently in order to elucidate white matter fibre orientations. Since these algorithms are based on the diffusion- weighted signal profile, the estimations are affected by noise artefacts. The proven robustness of these methods cannot counteract distortions since the statistical Rician behavior has not been taken into account. In this study, two techniques to counteract the noise distortions are presented to improve the fibre orientation estimations. Simulations and in vivo experiments show an improvement in the angular resolution and convergence of the results. One of these strategies represents a good compromise between computational cost and result improvements.
Keywords :
biological tissues; biomedical MRI; brain; image denoising; image resolution; medical image processing; Rician distributed data; angular resolution; complex tissue microstructure estimators; diffusion-weighted signal profile; fibre orientation estimators; noise artefacts; noise correction; white matter fibre orientations; Deconvolution; Diffusion tensor imaging; High-resolution imaging; Image resolution; In vivo; Microstructure; Noise robustness; Nuclear medicine; Rician channels; Tensile stress; DTI; Diffusion tensor imaging (DTI); HARDI; Rician noise; high angular resolution diffusion imaging (HARDI); orientation estimators; Algorithms; Artifacts; Artificial Intelligence; Brain; Data Interpretation, Statistical; Diffusion Magnetic Resonance Imaging; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Models, Anatomic; Models, Neurological; Models, Statistical; Nerve Fibers, Myelinated; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2008.920615