Title :
A New Instrument Designed to Measure the Magnetic Susceptibility of Human Liver Tissue In Vivo
Author :
Farrell, D.E. ; Allen, C.J. ; Whilden, M.W. ; Kidane, T.K. ; Baig, T.N. ; Tripp, J.H. ; Brown, R.W. ; Sheth, S. ; Brittenham, G.M.
Author_Institution :
Case Western Reserve Univ., Cleveland
Abstract :
All existing superconducting instrumentation for measuring the concentration of iron stored in the human liver requires liquid helium for its operation. We report the mathematical modeling, optimization, and instrumental performance of an instrument that uses high-transition-temperature (high-Tc) superconductors. Requiring only liquid nitrogen to operate, the susceptometer represents the first medical application of the phenomenon of high-temperature superconductivity with the potential for widespread clinical utility.
Keywords :
biomedical equipment; chemical variables measurement; high-temperature superconductors; iron; liver; magnetic susceptibility; optimisation; Fe; high transition temperature superconductors; human liver tissue in vivo; iron concentration measurement; liquid helium; liquid nitrogen; magnetic susceptibility; medical application; optimization; superconducting instrumentation; susceptometer; Helium; High temperature superconductors; Humans; In vivo; Instruments; Iron; Liver; Magnetic susceptibility; Mathematical model; Nitrogen; Diamagnetic; hepatic iron concentration; high-temperature superconductivity; magnetic susceptibility; paramagnetic; phantom; storage iron; susceptometer;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2007.901352
