Title :
An in vitro tissue model for evaluating the effect of carboxyhemoglobin concentration on pulse oximetry
Author :
Mendelson, Yitzhak ; Kent, Joel C.
Author_Institution :
Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA
fDate :
6/1/1989 12:00:00 AM
Abstract :
An in vitro tissue model for specific application to noninvasive transmittance pulse oximetry is discussed. The model was used to assess the effect of variations in carboxyhemoglobin concentration on noninvasive measurements of arterial hemoglobin oxygen saturation. The model is also potentially useful for assessing the effect on the accuracy of noninvasive pulse oximeters of other physiological and physical variables, such as blood hemocrit, methemoglobin concentration, arterial blood pulsations, blood temperature, and variations in the peak emission wavelengths of the LEDs in the optical sensor.
Keywords :
biomedical equipment; biomedical measurement; blood; LED peak emission wavelength; arterial blood pulsations; blood hemocrit; blood temperature; carboxyhaemoglobin concentration effect; in vitro tissue model; methemoglobin concentration; pulse oximetry; Biological system modeling; Biological tissues; Biomedical optical imaging; Blood; In vitro; In vivo; Infrared heating; Optical pulses; Predictive models; Pulse measurements; Carboxyhemoglobin; Humans; Models, Structural; Oximetry; Oxygen;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
