Excimer laser angioplasty: Tissue ablation, arterial response, and fiber optic delivery

Author

Singleton, Donald L. ; Paraskevopoulos, George ; Taylor, Roderick S. ; Higginson, Lyall A J

Author_Institution

National Research Council of Canada, Ottawa, Ontario, Canada

Volume

23

Issue

10

fYear

1987

fDate

10/1/1987 12:00:00 AM

Firstpage

1772

Lastpage

1782

Abstract

The results of recent work directed towards the application of excimer lasers to angioplasty are presented. Several laser-tissue interactions are examined, including the effect of the XeCl laser optical pulse duration (7-300 ns) on the threshold fluence for ablation of arterial wall and on the quality of the cut in human postmortem artery, the potential for altering the ablation threshold fluence of arterial plaque in swine by treatment with hematoporphyrin derivative, and the healing response of swine arterial wall to surgical irradiation with an argon laser and a pulsed XeCl laser. The dependence of damage thresholds and transmission properties of selected commercial fused silica fibers on the laser pulsewidth and wavelength are determined.

Keywords

Blood vessels; Laser biomedical applications; Noble-gas lasers, excimer; Angioplasty; Arteries; Fiber lasers; Humans; Laser ablation; Laser applications; Laser beam cutting; Laser surgery; Optical fibers; Optical pulses;

fLanguage

English

Journal_Title

Quantum Electronics, IEEE Journal of

Publisher

ieee

ISSN

0018-9197

Type

jour

DOI

10.1109/JQE.1987.1073231

Filename

1073231