Ionisation of dielectric spheroid membranes: a balloon model of electroporation of biological cells

Author

Gaynor, P.T. ; Bodger, P.S.

Author_Institution

Dept. of Electr. & Electron. Eng., Canterbury Univ., Christchurch, New Zealand

Volume

141

Issue

3

fYear

1994

fDate

5/1/1994 12:00:00 AM

Firstpage

190

Lastpage

196

Abstract

Analysis of the physical, optical and electrical aspects of voltage impulse dielectric breakdown in rubber membrane spheroids shows a spatial organisation of material ionisation, resulting in hole formation. The morphology of this breakdown is much like the dielectric breakdown of a biological cell membrane under electrical impulse conditions, commonly called electropermeabilisation or electroporation. A study of these breakdown systems indicates a possible mechanism of biological electropermeabilisation based on material ionisation

Keywords

bioelectric phenomena; biological techniques and instruments; biomembranes; cellular biophysics; dielectric materials; electric breakdown of solids; ionisation of solids; physiological models; rubber; balloon model; balloon model theory; biological cell membrane; biological electropermeabilisation; dielectric spheroid membranes; electrical impulse conditions; electroporation; electroporation of biological cells; hole formation; material ionisation; microscopy; morphology; photographic photon capture; photography; rubber membrane spheroids; voltage impulse dielectric breakdown;

fLanguage

English

Journal_Title

Science, Measurement and Technology, IEE Proceedings -

Publisher

iet

ISSN

1350-2344

Type

jour

DOI

10.1049/ip-smt:19949851

Filename

295440