Title :
Near infrared optical applications in molecular imaging
Author_Institution :
Center for Molecular Imaging Res., Massachusetts Gen. Hosp., Charlestown, MA, USA
Abstract :
Near infrared (NIR) optical imaging is a rapidly expanding newer technique that has combined research involving in vivo imaging technologies with research involving imaging probe design to help noninvasively evaluate important molecular events in vivo. This review details some of the advances in these areas that have allowed imaging of proteases, apoptosis, and cell surface receptors and details applications in diseases such as cancer, cardiovascular disease, and rheumatoid arthritis.
Keywords :
biomedical optical imaging; cancer; cardiovascular system; enzymes; molecular biophysics; reviews; apoptosis; cancer; cardiovascular disease; cell surface receptors; diseases; in vivo imaging technologies; molecular imaging; near infrared optical imaging; proteases; review; rheumatoid arthritis; Arthritis; Cancer; Cardiac disease; Cardiovascular diseases; In vivo; Infrared imaging; Molecular imaging; Optical design; Optical imaging; Probes;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2004.1337950
