Title :
Evaluation of MR-Induced Hot Spots for Different Temporal SAR Modes Using a Time-Dependent Finite Difference Method With Explicit Temperature Gradient Treatment
Author :
Nadobny, Jacek ; Szimtenings, Michael ; Diehl, Dirk ; Stetter, Eckart ; Brinker, Gerhard ; Wust, Peter
Abstract :
An investigation of magnetic resonance (MR)-induced hot spots in a high-resolution human model is performed, motivated by safety aspects for the use of MR tomographs. The human model is placed in an MR whole body resonator that is driven in a quadrature excitation mode. The MR-induced hot spots are studied by varying the following: the temporal specific absorption rate (SAR) mode (ldquosteady imagingrdquo, ldquointermittent imagingrdquo), the simulation procedure (related to given power levels or to limiting temperatures), and different thermal tissue properties including temperature-independent and temperature-dependent perfusion models. Both electromagnetic and thermodynamic simulations have been performed. For the electromagnetic modeling, a commercial finite-integration theory (FIT) code is applied. For the thermodynamic modeling, a time-domain finite-difference (FD) scheme is formulated that uses an explicit treatment of temperature gradient components. This allows a flux-vector-based implementation of heat transfer boundary conditions on cubical faces. It is shown that this FD scheme significantly reduces the staircase errors at thermal boundaries that are locally sloped or curved with respect to the cubical grid elements.
Keywords :
biological tissues; biomagnetism; biomedical MRI; biothermics; finite difference time-domain analysis; heat transfer; MR tomographs; MR-induced hot spots; finite-integration theory; heat transfer boundary conditions; magnetic resonance; quadrature excitation mode; temperature gradient treatment; temperature-independent perfusion models; temporal SAR modes; temporal specific absorption rate; thermal tissue properties; thermodynamic simulations; time-dependent finite difference method; time-domain finite-difference scheme; Biological system modeling; Electromagnetic modeling; Finite difference methods; Humans; Magnetic resonance; Safety; Specific absorption rate; Temperature; Thermodynamics; Time domain analysis; Bioheat transfer equation (BHTE); International Electrotechnical Commission (IEC) standard; finite difference (FD); heat transfer coefficient; magnetic resonance (MR); specific absorption rate (SAR); temperature-dependent perfusion; Algorithms; Body Burden; Computer Simulation; Fever; Finite Element Analysis; Humans; Magnetic Resonance Imaging; Models, Biological; Radiation Dosage; Relative Biological Effectiveness; Risk Assessment; Risk Factors; Whole Body Imaging;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2007.893499