Setup and Validation of an MPI Signal Chain for a Drive Field Frequency of 150 kHz

Author

Sattel, Timo F. ; Woywode, Oliver ; Weizenecker, Jurgen ; Rahmer, Jurgen ; Gleich, Bernhard ; Borgert, Jorn

Author_Institution

Philips Med. Syst. DMC GmbH, Hamburg, Germany

Volume

51

Issue

2

fYear

2015

fDate

Feb. 2015

Firstpage

1

Lastpage

3

Abstract

In this paper, an imaging system is considered, which is part of an activity to test the feasibility of clinical (whole-body) magnetic particle imaging (MPI). Recent studies on nerve stimulation in humans indicate that drive field amplitudes have to be limited to lower values compared with preclinical MPI. Since nerve stimulation thresholds increase with frequency, the drive field frequency for the clinical demonstrator is set to 150 kHz. To date, available MPI systems usually apply drive fields at frequencies ranging from 1 to 25 kHz. We report on the technical feasibility of a signal chain setup for a drive field frequency of 150 kHz.

Keywords

biomedical equipment; biomedical imaging; magnetic particles; MPI signal chain; clinical demonstrator; clinical magnetic particle imaging; drive field amplitudes; drive field frequency; frequency 150 kHz; imaging system; nerve stimulation thresholds; Band-pass filters; Capacitors; Coils; Damping; Harmonic analysis; Imaging; Magnetic particles; Magnetic particle imaging (MPI); signal chain;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2014.2326256

Filename

7067537