• DocumentCode
    115005
  • Title

    Stability analysis of PDEs modelling cell dynamics in Acute Myeloid Leukemia

  • Author

    Avila, J.L. ; Bonnet, C. ; Fridman, E. ; Mazenc, F. ; Clairambault, J.

  • Author_Institution
    Equipe DISCO, Inria, Gif-sur-Yvette, France
  • fYear
    2014
  • fDate
    15-17 Dec. 2014
  • Firstpage
    3059
  • Lastpage
    3064
  • Abstract
    In this paper we perform a stability analysis of two systems of partial differential equations (PDEs) modelling cell dynamics in Acute Myeloid Leukemia. By using a Lyapunov approach, for an equilibrium point of interest, we obtain stability bounds depending on the parameters of the systems. First, we derive sufficient conditions for boundedness of solutions. Then, asymptotic stability conditions are obtained. The results are illustrated with numerical examples and simulations.
  • Keywords
    Lyapunov methods; asymptotic stability; blood; cancer; cellular biophysics; partial differential equations; Lyapunov approach; PDE; acute myeloid leukemia; asymptotic stability conditions; cell dynamics modelling; partial differential equations; solution boundedness; stability analysis; stability bounds; sufficient conditions; Analytical models; Cancer; Mathematical model; Sociology; Stability analysis; Statistics; Trajectory;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Decision and Control (CDC), 2014 IEEE 53rd Annual Conference on
  • Conference_Location
    Los Angeles, CA
  • Print_ISBN
    978-1-4799-7746-8
  • Type

    conf

  • DOI
    10.1109/CDC.2014.7039860
  • Filename
    7039860