Title :
Large deformation diffeomorphic metric mapping of vector fields
Author :
Cao, Yan ; Miller, Michael I. ; Winslow, Raimond L. ; Younes, Laurent
Author_Institution :
Center for Imaging Sci., Johns Hopkins Univ., Baltimore, MD, USA
Abstract :
This paper proposes a method to match diffusion tensor magnetic resonance images (DT-MRIs) through the large deformation diffeomorphic metric mapping of vector fields, focusing on the fiber orientations, considered as unit vector fields on the image volume. We study a suitable action of diffeomorphisms on such vector fields, and provide an extension of the Large Deformation Diffeomorphic Metric Mapping framework to this type of dataset, resulting in optimizing for geodesics on the space of diffeomorphisms connecting two images. Existence of the minimizers under smoothness assumptions on the compared vector fields is proved, and coarse to fine hierarchical strategies are detailed, to reduce both ambiguities and computation load. This is illustrated by numerical experiments on DT-MRI heart images.
Keywords :
biodiffusion; biomedical MRI; cardiology; deformation; differential geometry; image matching; medical image processing; vectors; DT-MRI heart images; diffeomorphic metric mapping; diffeomorphisms; diffusion tensor; fiber orientations; geodesics; large deformation mapping; magnetic resonance images; vector fields; Biological tissues; Biomedical engineering; Biomedical imaging; Cardiac disease; Cardiovascular diseases; Diffusion tensor imaging; Heart; Magnetic resonance; Magnetic resonance imaging; Tensile stress; Diffeomorphism; diffusion tensor MRI; image registration; variational methods; vector field; Algorithms; Alzheimer Disease; Artificial Intelligence; Dementia; Discriminant Analysis; Hippocampus; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2005.853923