DocumentCode
1156912
Title
High Spatial Resolution in
-Imaging With a PIM Device
Author
Donnard, Jerome ; Thers, Dominique ; Servagent, Noel ; Luquin, Lionel
Author_Institution
SUBATECH Ecole des Mines de Nantes, Univ. de Nantes, Nantes
Volume
56
Issue
1
fYear
2009
Firstpage
197
Lastpage
200
Abstract
The autoradiography is an imaging technique able to locate in 2 dimensions molecules labeled with beta radioactive emitters. The usual technique in use is based on solid device, mostly films or phosphor screens. We report on tests performed with PIM (parallel ionization multiplier) on microscope slides demonstrating that MPGD (micro pattern gas detector) incorporating micromegas micro-meshes have to be considered for a next generation of beta-imager. The main advantages come from the high spatial resolution measured (25 mum FWHM in two dimensions) and from the event by event reconstruction position measurement resulting in ldquoon-linerdquo imaging availability in which no ldquoafter developmentrdquo have to be performed.
Keywords
biomedical imaging; position measurement; radioisotope imaging; 2-dimension molecules; MPGD; PIM; autoradiography; beta radioactive emitters; beta-imaging; high spatial resolution; micropattern gas detector; microscope slides; parallel ionization multiplier; phosphor screens; position measurement; solid device; Gas detectors; High-resolution imaging; Ionization; Microscopy; Performance evaluation; Phosphors; Position measurement; Solids; Spatial resolution; Testing; Beta autoradiography; MPGD; PIM; beta rays; medical imaging;
fLanguage
English
Journal_Title
Nuclear Science, IEEE Transactions on
Publisher
ieee
ISSN
0018-9499
Type
jour
DOI
10.1109/TNS.2008.2005673
Filename
4782145
Link To Document