DocumentCode
1170081
Title
Implementation of a water compensator for total body irradiation
Author
Gallina, Paolo ; Rosati, Giulio ; Rossi, Aldo
Author_Institution
Dept. of Energetics, Univ. of Trieste, Italy
Volume
52
Issue
10
fYear
2005
Firstpage
1741
Lastpage
1747
Abstract
This paper presents the design, implementation, and testing of an integrated system for improving dose homogeneity in total body irradiation (TBI). TBI is a radiation therapy technique that consists in delivering a uniform X-ray dose to the entire body of the patient. Because of variations in patient´s tissues thickness and density, achieving a uniform dose over the entire body is one of the major challenges in TBI. The system proposed in this paper, whose main goal is to compensate for tissues heterogeneities, is made up of a translating bed, a linear accelerator, a vision system for body thickness assessment, a dynamically controlled water filter, and a main control unit. The water filter, placed between the X-ray source and the patient, is made up of an array of 70 small water containers (cells). The water level in each cell is controlled in real time, so as to modify the dose distribution both in the transverse direction and in the longitudinal direction. A prototype of the water filter system was implemented and tested, achieving good results in terms of dose uniformity.
Keywords
biological tissues; dosimetry; linear accelerators; radiation therapy; dose distribution; dose homogeneity; dynamically controlled water filter; linear accelerator; patient tissue density; patient tissue thickness; radiation therapy; tissue heterogeneity; total body irradiation; translating bed; uniform X-ray dose; vision system; water compensator; Biomedical applications of radiation; Containers; Control systems; Linear accelerators; Machine vision; Nonlinear filters; Prototypes; System testing; Thickness control; Water resources; Level control; X-ray applications; total body irradiation; water; Beds; Body Burden; Equipment Design; Equipment Failure Analysis; Radiometry; Radiotherapy Dosage; Radiotherapy, Computer-Assisted; Relative Biological Effectiveness; Systems Integration; Water; Whole-Body Irradiation;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2005.855715
Filename
1510857
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