Title :
Cost-reducing protein production and delivery for sexually transmitted disease prevention
Author :
Saltzman, Mark W.
Author_Institution :
Biomed. Eng. Program, Yale Univ., New Haven, CT, USA
Abstract :
Discusses producing vaccines and antibody proteins from plants with "green vaccines". In passive immunization, antibodies are produced outside the body and manufactured to be active against a specific pathogen (such as herpes virus). With active immunization, one of the major obstacles to cost-reduction is the identification of inexpensive but effective methods for converting the plant cells or tissues into an orally active formulation.
Keywords :
botany; diseases; patient treatment; proteins; active immunization; antibody proteins; cost-reducing protein production; herpes virus; orally active formulation; plant cells; plant tissues; protein delivery; sexually transmitted disease prevention; specific pathogen; vaccines; Biological system modeling; Chemical engineering; Diseases; Immune system; Mice; Plants (biology); Polymers; Production; Proteins; Vaccines;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2003.1191448