Title :
A quantitative analysis of 3-D coronary modeling from two or more projection images
Author :
Movassaghi, B. ; Rasche, V. ; Grass, M. ; Viergever, M.A. ; Niessen, W.J.
Author_Institution :
Philips Res. Labs., Hamburg, Germany
Abstract :
A method is introduced to examine the geometrical accuracy of the three-dimensional (3-D) representation of coronary arteries from multiple (two and more) calibrated two-dimensional (2-D) angiographic projections. When involving more then two projections, (multiprojection modeling) a novel procedure is presented that consists of fully automated centerline and width determination in all available projections based on the information provided by the semi-automated centerline detection in two initial calibrated projections. The accuracy of the 3-D coronary modeling approach is determined by a quantitative examination of the 3-D centerline point position and the 3-D cross sectional area of the reconstructed objects. The measurements are based on the analysis of calibrated phantom and calibrated coronary 2-D projection data. From this analysis a confidence region (α°≈[35°-145°]) for the angular distance of two initial projection images is determined for which the modeling procedure is sufficiently accurate for the applied system. Within this angular border range the centerline position error is less then 0.8 mm, in terms of the Euclidean distance to a predefined ground truth. When involving more projections using our new procedure, experiments show that when the initial pair of projection images has an angular distance in the range α°≈[35°-145°], the centerlines in all other projections (γ=0°-180°) were indicated very precisely without any additional centering procedure. When involving additional projection images in the modeling procedure a more realistic shape of the structure can be provided. In case of the concave segment, however, the involvement of multiple projections does not necessarily provide a more realistic shape of the reconstructed structure.
Keywords :
blood vessels; cardiology; diagnostic radiography; medical image processing; phantoms; physiological models; 3-D coronary modeling; Euclidean distance; automated centerline determination; automated width determination; coronary arteries; multiple calibrated two-dimensional angiographic projections; multiprojection modeling; phantom; Angiography; Arteries; Associate members; Data analysis; Image analysis; Image reconstruction; Image segmentation; Imaging phantoms; Shape; Two dimensional displays; 3-D quantification; 3-D-modeling; Angiography; multiprojection; Algorithms; Animals; Artificial Intelligence; Computer Simulation; Coronary Angiography; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Information Storage and Retrieval; Models, Anatomic; Models, Cardiovascular; Numerical Analysis, Computer-Assisted; Pattern Recognition, Automated; Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Subtraction Technique; Swine;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2004.837340