Title :
Continuous Turbidimetric Analysis of pH Dependent Biological Coalescence Processes
Author :
Ryan, D.P. ; Kolin, A.
Author_Institution :
Department of Biophysics and Nuclear Medicine, University of California, Los Angeles, Calif.
fDate :
7/1/1964 12:00:00 AM
Abstract :
The method described allows rapid analysis, by pH modulation, of the coalescence of small samples of biological materials in dilute suspensions. Specifically, agglutination of various species of viruses and bacteria at their isoelectric points, and the polymerization process of the muscle protein actin are investigated. A typical time of analysis is 20 sec, and 5 ml of suspensions as dilute as 0.2 mg/ml are sufficient for most viruses investigated.
Keywords :
Biological materials; Biomedical optical imaging; Calibration; Electrodes; Microorganisms; Muscles; Polymers; Proteins; Suspensions; Viruses (medical); Bacteria; Biological Products; Chemistry, Analytical; Hydrogen-Ion Concentration; Muscle Proteins; Viruses;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1964.4502314
