Title :
Microelectrode array on folding polyimide ribbon for epidural mapping of functional evoked potentials
Author :
Takahashi, Hirokazu ; Ejiri, Takayuki ; Nakao, Masayuki ; Nakamura, Naoya ; Kaga, Kimitaka ; Hervé, Thierry
Author_Institution :
Dept. of Eng. Synthesis, Univ. of Tokyo, Japan
fDate :
4/1/2003 12:00:00 AM
Abstract :
This paper describes a flexible polyimide microelectrode ribbon with a bending structure for epidural recording. Bending the ribbon establishes good electro-mechanical contact of the electrodes to the cortex. Impedance spectroscopy and noise measurements in vitro were used to characterize the electrodes. Our in vivo experiments then successfully achieved synchronized neuronal activity and evoked potential patterns useful for understanding brain function and for finding cortical function.
Keywords :
arrays; auditory evoked potentials; biological techniques; microelectrodes; prosthetics; auditory cortex; brain function understanding; cortical function finding; epidural mapping; folding polyimide ribbon; functional evoked potentials; good electro-mechanical contact; impedance spectroscopy; in vivo experiments; microelectrode array; neural interface; neuroprosthetics; noise measurements; synchronized neuronal activity; tonotopic organization; Electrochemical impedance spectroscopy; Electrodes; In vitro; In vivo; Microelectrodes; Neurophysiology; Noise measurement; Polyimides; Spatial resolution; Surgery; Action Potentials; Animals; Auditory Cortex; Biocompatible Materials; Brain Mapping; Electrodes, Implanted; Electroencephalography; Epidural Space; Equipment Design; Evoked Potentials, Auditory; Microelectrodes; Nerve Net; Neurons; Rats; Rats, Wistar; Resins, Synthetic;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2003.809483