DNA sensors with impedimetric and magnetoresistive transduction — A comparison study

Author

Ameer, Zoobia ; Primiceri, E. ; De Feo, F. ; Chiriaco, M.S. ; Monteduro, A.G. ; Maruccio, G. ; Rinaldi, Rinaldo

Author_Institution

NNL, Ist. Nanosci., Lecce, Italy

fYear

2014

fDate

14-18 Jan. 2014

Firstpage

65

Lastpage

68

Abstract

Development of lab-on-chip devices attracted large interest for detection of specific analyte/markers, cellular studies and drug screening. In the case of DNA, one of the biggest problems is the low concentration of target sequences in biological samples, which is the reason for typical use of amplification steps. In this paper, we discuss our results in developing DNA sensors integrated with microfluidic components in biochips for DNA recognition. Two different approaches are investigated and compared which are based respectively on impedance and magnetoresistive transduction.

Keywords

DNA; bioMEMS; bioelectric potentials; biosensors; cellular biophysics; lab-on-a-chip; magnetoresistance; microfluidics; microsensors; molecular biophysics; molecular configurations; DNA recognition; DNA sensors; analyte-markers detection; biological sample; cellular studies; drug screening; impedance; impedimetric transduction; lab-on-chip devices; magnetoresistive transduction; microfluidic components; Biosensors; DNA; Impedance; Magnetic sensors; Magnetoresistance; Probes;

fLanguage

English

Publisher

ieee

Conference_Titel

Applied Sciences and Technology (IBCAST), 2014 11th International Bhurban Conference on

Conference_Location

Islamabad

Type

conf

DOI

10.1109/IBCAST.2014.6778122

Filename

6778122