Title :
On Nakhleh´s Metric for Reduced Phylogenetic Networks
Author :
Cardona, Gabriel ; Llabré, Mercè ; Rosselló, Francesc ; Valiente, Gabriel
Author_Institution :
Dept. of Math. & Comput. Sci., Univ. of the Balearic Islands, Palma de-Mallorca, Spain
Abstract :
We prove that Nakhleh´s metric for reduced phylogenetic networks is also a metric on the classes of tree-child phylogenetic networks, semibinary tree-sibling time consistent phylogenetic networks, and multilabeled phylogenetic trees. We also prove that it separates distinguishable phylogenetic networks. In this way, it becomes the strongest dissimilarity measure for phylogenetic networks available so far. Furthermore, we propose a generalization of that metric that separates arbitrary phylogenetic networks.
Keywords :
biology computing; genetics; trees (mathematics); Nakhleh metric; reduced phylogenetic networks; Biology and genetics; graph algorithms; network problems.; Algorithms; Animals; Computational Biology; Evolution, Molecular; Humans; Models, Genetic; Models, Theoretical; Nucleic Acid Hybridization; Phylogeny; Recombination, Genetic; Sequence Alignment; Sequence Analysis, DNA;
Journal_Title :
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
DOI :
10.1109/TCBB.2009.33