Title :
Evaluation of new complexes of biocompatible magnetic fluid and third generation of photosensitizer useful to cancer treatment
Author :
Macaroff, P.P. ; Oliveira, D.M. ; Ribeiro, K.F. ; Lacava, Z.G.M. ; Lima, E.C.D. ; Morais, P.C. ; Tedesco, A.C.
Author_Institution :
Univ. de Sao Paulo, Ribeirao Preto, Brazil
Abstract :
In this study, we performed in vitro evaluation of the dark and light toxicity of a third-generation photosensitizer (PS), a biocompatible magnetic fluid (BMFs), and the BMF/PS complex using the J774-A cell line. The BMFs used is based on maghemite nanoparticles surface-coated with phosphate whereas for photosensitizer the Chlorine e6 (Chle6) was employed.
Keywords :
cancer; magnetic fluids; magnetic particles; nanoparticles; patient treatment; photochemistry; BMF/PS complex; J774-A cell line; biocompatible magnetic fluid; cancer treatment; dark/light toxicity; maghemite nanoparticles; photodynamic therapy; photosensitizer; Biological materials; Cancer; Drugs; In vitro; Magnetic liquids; Magnetic materials; Medical treatment; Nanoparticles; Protocols; Surface treatment; Magnetic fluid; photodynamic therapy; photosensitizer (PS);
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2005.855353
