Diamagnetic properties of fibrin and fibrinogen

Author

Iwasaka, Masakazu ; Ueno, Shoogo ; Tsuda, Hiroko

Author_Institution

Inst. of Med. Electron., Tokyo Univ., Japan

Volume

30

Issue

6

fYear

1994

fDate

11/1/1994 12:00:00 AM

Firstpage

4695

Lastpage

4697

Abstract

The authors have observed that the fibrinolytic process in strong magnetic fields up to 8 T was enhanced. Here they focused on the mechanism of this phenomenon. First, they observed that gradient magnetic fields eroded a fibrin gel in a specific direction. Next the authors carried out an experiment to measure concentrations of fibrin in magnetic fields up to 8 T. They measured levels of fibrin degradation products by colorimetric determination and concluded that changes in concentrations of fibrin polymers occurred in gradient magnetic fields up to 8 T. Also, by measuring transmittance at 500 nm of fibrin gels, the authors investigated the effects of magnetically formed structures of fibrin polymers on the dissolution of fibrin gels. The magnetic orientation of fibrin remained in the fibrinolytic process after coagulating in an 8 T magnetic field

Keywords

biological effects of fields; biomagnetism; biomolecular effects of radiation; coagulation; colorimetry; diamagnetic materials; dissolving; gels; proteins; 500 nm; 8 T; coagulation; colorimetric determination; diamagnetic properties; dissolution; fibrin degradation products; fibrin gel; fibrin polymers; fibrinogen; fibrinolytic process; gradient magnetic fields; macromolecule concentration; magnetic orientation; magnetically formed structures; strong magnetic fields; transmittance; Biomedical engineering; Blood vessels; Boring; Computer science; Laboratories; Magnetic field measurement; Magnetic fields; Magnetic materials; Polymer gels; Superconducting magnets;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/20.334192

Filename

334192