Title :
Diffusion Effects of Liquid-Filled Micropipettes: A Pseudobinary Analysis of Electrolyte Leakage
Author :
Geisler, C.Daniel ; Lightfoot, Edwin N. ; Schmidt, Frank P. ; Sy, Francisco
Author_Institution :
Department of Electrical Engineering and the Laboratory of Neurophysiology, University of Wisconsin, Madison, Wis.
Abstract :
The importance of diffusion phenomena in glass micropipettes filled with concentrated electrolyte solutions is well known. Nonequilibrium diffusion-rate equations for electrolyte-filled glass micropipettes are given for a model of situations of current interest: diffusion into an infinite medium. The solutions of these equations give the flux of material out of a micropipette as a function of time, concentration, and geometry.
Keywords :
Chemical engineering; Circuits; Electrodes; Electrophysiology; Equations; Filtering; Geometry; Glass; Laboratories; Neurophysiology; Diffusion; Electrolytes; Mathematics; Models, Chemical; Time Factors;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1972.324141