The Electrodeacidification of Blood

The design parameters for blood electrodeacidification were determined experimentally with due consideration of the physical properties of the diffusion of hydrogen through palladium (Pd) membrane electrodes, along with the physiological aspects of hemodialysis and electrohemodialysis for acidosis. Several models of an electrodeacidifier for extracorporeally circulating blood were built. Initial designs showed difficulties with clotting of heparinized blood and excessive hemolysis, but no evidence of membrane fouling. In subsequent experiments the clotting problem was eliminated by the interposition of anion exchange membranes between the blood and the Pd black surface.