• DocumentCode
    1203352
  • Title

    Estimation of Circulating Blood Volume from a Tracer-Response Curve

  • Author

    Weinstein, Herbert ; Fu, Benedict S. ; Acosta, Raul ; Bernstein, Barry ; Shaffer, Aaron B.

  • Author_Institution
    Department of Chemical Engineering, Illinois Institute of Technology, Chicago, Ill. 60616, on leave at the Department of Mechanical Engineering, Technion-Israel Institute of Technology, Haifa, Israel.
  • Issue
    4
  • fYear
    1973
  • fDate
    7/1/1973 12:00:00 AM
  • Firstpage
    269
  • Lastpage
    277
  • Abstract
    A method is developed for analyzing sudden injection dye (tracer) curves in order to obtain the distribution of first passage times in the mammalian circulation. The moments of the distribution yield useful quantities such as circulating blood volume. The method involves the use of Liouville-Neumann series. The calculation of the first passage time distribution (FPD) also requires a deconvolution through the use of Fourier transforms, but the calculation of moments does not.
  • Keywords
    Biomedical measurements; Blood; Chemical engineering; Chemical technology; Dogs; Hemorrhaging; Integral equations; Sampling methods; Time measurement; Volume measurement; Animals; Blood Volume; Dogs; Dye Dilution Technique; Mathematics; Monitoring, Physiologic; Shock, Hemorrhagic; Time Factors;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.1973.324191
  • Filename
    4120643