Title :
Mathematical Modeling of Pulmonary Airway Dynamics
Author :
Golden, James F. ; Clark, John W., Jr. ; Stevens, Paul M.
Author_Institution :
Department of Engineering Biophysics, University of Alabama, Birmingham, Ala. 35294.
Abstract :
A mathematical model has been derived that describes the pressure-flow relationship in the ventilatory system under conditions of constant lung volume. The parameters of the model include small airway resistance, large airway resistance, and lung elastic recoil. A collapsible airway segment is included to model compression of the airways during expiration.
Keywords :
Biomedical engineering; Diseases; Humans; Immune system; Least squares approximation; Lungs; Mathematical model; Mouth; Parameter estimation; Predictive models; Airway Obstruction; Humans; Lung Diseases, Obstructive; Mathematics; Models, Biological; Pressure; Pulmonary Ventilation; Ventilation-Perfusion Ratio;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1973.324211
