• DocumentCode
    1207477
  • Title

    Synthetic skin

  • Author

    Leventon, W.

  • Volume
    39
  • Issue
    12
  • fYear
    2002
  • Firstpage
    28
  • Lastpage
    33
  • Abstract
    Biomedical science has made a lot of progress in understanding how cells grow into functioning tissue and what chemical and other cues they need to do it right. Tissue engineering is the application of that knowledge to the building or repairing of organs, including skin, the largest organ in the body. Generally, engineered tissue is a combination of living cells and a support structure called a scaffold. The scaffold, depending on the organ in production, can be anything from a matrix of collagen, a structural protein, to synthetic biodegradable plastic laced with chemicals that stimulate cell growth and multiplication. The "seed" cells that initiate this propagation come from laboratory cultures or from the patient\´s own body. For future ventures to succeed, precise sensors and control systems will be needed to create and maintain the biochemical and mechanical environments that nurture tissues like skin. Also, robotics and other automation will be needed to remove people from the tissue growth process. Already, fledgling firms and tissue engineering labs are borrowing some advanced engineering practices, like high-precision rapid prototyping and photolithography, as they strive to create engineered bone, cartilage, blood vessels, and internal organs.
  • Keywords
    biomedical materials; cellular biophysics; skin; automation; biochemical environments; biomedical science; cell growth; control systems; high-precision rapid prototyping; living cells; mechanical environments; photolithography; robotics; sensors; support structure; synthetic skin manufacture; tissue engineering; Biodegradable materials; Chemicals; Design engineering; Plastics; Protein engineering; Robotics and automation; Skin; Tissue engineering;
  • fLanguage
    English
  • Journal_Title
    Spectrum, IEEE
  • Publisher
    ieee
  • ISSN
    0018-9235
  • Type

    jour

  • DOI
    10.1109/MSPEC.2002.1088442
  • Filename
    1088442