Title :
The Use of Laguerre Functions for Parameter Identification in a Distributed Biological System
Author :
Salcudean, S.E. ; Bélanger, Pierre R. ; Goresky, Carl A. ; Rose, Colin P.
Author_Institution :
Electrical Engineering Program, University of California
Abstract :
A new identification algorithm for a class of distributed parameter systems is suggested. The model dealt with describes the passage through the microvascular bed of the liver of a radioactive tracer, initially equilibrated between red cells and plasma. Its purpose is to obtain information on the quantitative measure of permeabilities of the red cell membrane and liver cell surfaces facing the capillaries.
Keywords :
Biological systems; Biomembranes; Blood; Cells (biology); Extracellular; Frequency domain analysis; Liver; Parameter estimation; Permeability; Plasma confinement; Biomedical Engineering; Capillary Permeability; Erythrocytes; Humans; Liver; Liver Circulation; Models, Biological;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1981.324766
