Title :
Dielectric Properties of VX-2 Carcinoma Versus Normal Liver Tissue
Author :
Smith, Susan Rae ; Foster, Kenneth R. ; Wolf, Gerald L.
Author_Institution :
Department of Bioengineering, University of Pennsylvania
fDate :
5/1/1986 12:00:00 AM
Abstract :
The bulk electrical properties of an implanted VX-2 carcinoma in rabbit liver tissue were measured from 1 kHz to 13 MHz, together with those of normal rabbit liver tissue. At the lower end of the frequency range, the conductivity of the tumor tissue was 6-7.5 times higher and its permittivity was 2-5 times lower than that of the normal tissue. The increased conductivity of the tumor tissue is believed to arise from the presence of widespread necrosis in the tumor nodules. Such differences, if generally present between tumor and surrounding normal tissues, could be used to advantage in clinical applications of electromagnetic fields.
Keywords :
Biomedical measurements; Breast neoplasms; Conductivity; Dielectric measurements; Electric variables measurement; Electromagnetic fields; Frequency; Liver neoplasms; Permittivity; Rabbits; Animals; Cell Line; Electric Conductivity; Electric Stimulation; Liver; Liver Neoplasms, Experimental; Male; Rabbits;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1986.325740