Title :
A Method of Calculation for Simulation of Action Potentials
Author_Institution :
Department of Physics and Astronomy, Vanderbilt University
fDate :
6/1/1986 12:00:00 AM
Abstract :
A new method is presented of calculating digital computer simulations of propagating nerve or cardiac action potentials. The calculation is of the implicit type and is done with the "cable model" approach utilizing either well-known nerve or cardiac membrane physiological models. It does not require large computing resources for long fibers because it utilizes a "retarded potential" approach so that large matrix inversions are avoided and voltage profiles can be calculated with only eight spacesteps at one time.
Keywords :
Biomembranes; Computational modeling; Computer simulation; Equations; Heart; History; Nerve fibers; Numerical simulation; Optical fiber cables; Voltage; Action Potentials; Animals; Biomedical Engineering; Biometry; Models, Neurological; Neurons; Purkinje Fibers;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1986.325845