Title :
In Vivo Cardiac Muscle Perfusion: A New Measurement Method
Author :
McInerney, J.J. ; Copenhaver, G.L. ; Herr, M.D.
Author_Institution :
Department of Biomedical Engineering and the Division of Cardiology, Milton S. Hershey Medical Center, Pennsylvania State University
fDate :
3/1/1987 12:00:00 AM
Abstract :
A nonradioactive tracer technique for the evaluation of heart disease is presented. A microprocessor controlled scanning system is used to position a germanium detector such that it interrogates an isolated segment of myocardial tissue. Iodine based contrast agent in intravenously injected while irradiating the tissue segment with a low energy X-ray spot beam. X-ray induced iodine fluorescence of the passing contrast agent is then used to monitor the local tissue perfusion.
Keywords :
Cardiac disease; Control systems; Detectors; Fluorescence; Germanium; In vivo; Microprocessors; Monitoring; Muscles; Myocardium; Animals; Diatrizoate; Diatrizoate Meglumine; Dogs; Drug Combinations; Heart Diseases; Spectrometry, X-Ray Emission; Swine;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1987.325952
