Title :
Recent progress in microfluidic devices for nucleic acid and antibody assays
Author :
Selvaganapathy, Ponnambalam Ravi ; Carlen, Edwin T. ; Mastrangelo, Carlos H.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Michigan Univ., Ann Arbor, MI, USA
fDate :
6/1/2003 12:00:00 AM
Abstract :
Microfluidic devices are increasingly important in biomedical assays. In this paper, we review recent progress on these devices for chemical amplification, hybridization, separation, and detection of nucleic acids. Recent developments in microfluidic technologies for detection of protein binding events in immunoassay applications are also reviewed.
Keywords :
biological techniques; macromolecules; microfluidics; molecular biophysics; antibody assay; biomedical assay; chemical amplification; hybridization chip; microfluidic device; nucleic acid assay; protein binding immunoassay; separation microdevice; Biochemistry; Chemicals; DNA; Genetics; Immune system; Laboratories; Microfluidics; Micromechanical devices; Performance analysis; Proteins;
Journal_Title :
Proceedings of the IEEE
DOI :
10.1109/JPROC.2003.813569
