The Effects of Filtering the His-Purkinje System Electrocardiogram

Several laboratories have used signal averaging to record His-Purkinje system (HPS) potentials from the body surface of man as a means of noninvasive evaluation of intraventricular conduction. This study evaluated the use of a 0.3-300 Hz recording bandwidth as opposed to a bandwidth of 80-300 Hz most commonly used by other investigators. The wider bandwidth produced HPS recordings which were quite reproducible among eight normal subjects and showed marked changes in duration and configuration among twelve subjects with right or left bundle branch block. Comparisons were then made between analog filtered HPS waveforms and a digital differentiation algorithm. An explanation of the high frequency components of the HPS waveform is based on known properties of the HPS. This will aid in the development of models for implementing a forward or inverse solution for HPS potentials.