Design and imaging studies of a position sensitive photomultiplier based dynamic SPECT system

Author

Singh, Manbir ; Leahy, Richard ; Brechner, Ricardo ; Yan, Xiao-hong

Author_Institution

Dept. of Radiol., Univ. of Southern California, Los Angeles, CA, USA

Volume

36

Issue

1

fYear

1989

fDate

2/1/1989 12:00:00 AM

Firstpage

1132

Lastpage

1137

Abstract

The design and image reconstruction aspects of dynamic SPECT (single-photon-emission computed tomography) instrumentation utilizing multiple rings of position-sensitive photomultiplier tubes (PSPMTs) are reported. A diverging cone-beam collimator is attached to each PSPMT to achieve a 22-cm-diameter spherical field of view in a system designed for head imaging. The resolution with the diverging collimator is estimated to be approximately 20% worse than with a parallel hold collimator. Iterative and direct cone-beam reconstruction algorithms have been investigated under different conditions of angular sampling and counting statistics. The ramifications of temporal resolution and signal-to-noise ratio are discussed in relation to dynamic SPECT imaging of labeled cisplatin for chemotherapy

Keywords

biomedical equipment; computerised picture processing; computerised tomography; photomultipliers; radioisotope scanning and imaging; chemotherapy; cone-beam reconstruction algorithms; diverging cone-beam collimator; dynamic SPECT; head imaging; image reconstruction aspects; labeled cisplatin; parallel hold collimator; position-sensitive photomultiplier tubes; signal-to-noise ratio; single-photon-emission computed tomography; temporal resolution; Collimators; Computed tomography; Head; Image reconstruction; Instruments; Photomultipliers; Reconstruction algorithms; Sampling methods; Signal resolution; Statistics;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.34618

Filename

34618