Title :
Tissue spectroscopy with electrical impedance tomography: computer simulations
Author_Institution :
Inst. Nat. de la Sante et de la Recherche Med., Lyon, France
Abstract :
A method is proposed by which bioelectrical spectroscopy could be combined with electrical impedance tomography (EIT) to provide noninvasive characterization of tissue. Multifrequency (2-200 kHz) EIT measurements were simulated with a numerical model for a volume of porcine liver immersed in an electrolytic tank. From the reconstructed EIT images the tissue characterization method was then applied enabling a plot of complex resistivity to be drawn for any selected pixel in the image. Simulations were performed for a small volume of degraded tissue embedded in the normal tissue to examine its effect on the derived spectroscopic parameters. The method could have an application in transplant surgery for screening organs for tissue degradation.
Keywords :
digital simulation; electric impedance imaging; medical image processing; spectroscopy; 2 to 280 kHz; bioelectrical spectroscopy method; complex resistivity plot; degraded tissue; electrical impedance tomography; electrolytic tank immersion; medical imaging; noninvasive tissue characterization; normal tissue; organs screening; porcine liver; reconstructed images; tissue degradation; transplant surgery; Bioelectric phenomena; Computational modeling; Computer simulation; Degradation; Electrochemical impedance spectroscopy; Liver; Numerical models; Numerical simulation; Tomography; Volume measurement; Animals; Computer Simulation; Electric Impedance; Electrodes; Electrolysis; Electrophysiology; Liver; Models, Biological; Swine; Tomography;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
