Title :
Mean curvature mapping for detection of corneal shape abnormality
Author :
Tang, Maolong ; Shekhar, Raj ; Huang, David
Author_Institution :
Ohio State Univ., Columbus, OH, USA
fDate :
3/1/2005 12:00:00 AM
Abstract :
Corneal topography is used to measure the anterior surface of the cornea. It is conventionally represented as radial slope, radial curvature, and elevation. In this paper, we introduce the application of mean curvature mapping as an alternative representation of the corneal topography. The purpose is to improve the detection of keratoconus and other diseases characterized by local increase in corneal curvature. Both simulated keratoconic cornea and real keratoconus data exported from the corneal topography system were analyzed. Four representations of corneal topography were generated and compared. It was found that mean curvature mapping provided the most precise cone location in simulated keratoconus. In both actual and simulated keratoconus cases, the appearance of the cone-like distortion is more consistent on mean curvature maps. Mean curvature mapping may improve the detection and localization of corneal shape abnormalities.
Keywords :
biomedical optical imaging; diseases; eye; medical image processing; computerized videokeratography; corneal shape abnormality detection; corneal topography; disease detection; keratoconus detection; local corneal curvature increase; mean curvature mapping; Analytical models; Cornea; Diseases; Labeling; Lenses; Optical distortion; Optical refraction; Retina; Shape measurement; Surface topography; Cornea; corneal topography; keratoconus; mean curvature; Algorithms; Artificial Intelligence; Cluster Analysis; Cornea; Corneal Topography; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Information Storage and Retrieval; Keratoconus; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2004.843192