Three-dimensional reconstruction of in vivo blood vessels in human skin using phase-resolved optical Doppler tomography

Author

Zhao, Yonghua ; Brecke, Kjell Morten ; Ren, Hongwu ; Ding, Zhihua ; Nelson, J. Stuart ; Chen, Zhongping

Author_Institution

Center for Biophys. Eng., California Univ., Irvine, CA, USA

Volume

7

Issue

6

fYear

2001

Firstpage

931

Lastpage

935

Abstract

Phase-resolved optical Doppler tomography (ODT) has very high sensitivity while maintaining a fast axial scanning rate, making it possible to reconstruct blood flow in three dimensions. Here we demonstrate an ODT system that employed novel signal-processing techniques to remove aliasing effects and artifacts caused by lateral scanning and target movement. The results show that these techniques not only simplified ODT, but also improved lateral scanning speed. Using these signal-processing techniques, three-dimensional images of in vivo blood vessels in human skin were then reconstructed

Keywords

Doppler shift; Hilbert transforms; bio-optics; blood flow measurement; blood vessels; flow visualisation; image reconstruction; light interferometry; medical image processing; optical tomography; skin; 3D reconstruction; Doppler image processing; Hilbert transform; aliasing effects; artifacts; fast axial scanning rate; fringe phase difference; high sensitivity; human skin; in vivo blood vessels; low-coherence Michelson interferometry; optical coherence tomography; phase-resolved optical Doppler tomography; signal-processing techniques; target movement; Biomedical optical imaging; Blood flow; Blood vessels; Humans; Image reconstruction; In vivo; Optical imaging; Optical sensors; Skin; Tomography;

fLanguage

English

Journal_Title

Selected Topics in Quantum Electronics, IEEE Journal of

Publisher

ieee

ISSN

1077-260X

Type

jour

DOI

10.1109/2944.983296

Filename

983296