DocumentCode :
1268311
Title :
Planar Wave Propagation Through a Tapered Flagellated Nanoswimmer
Author :
Rathore, Jitendra Singh ; Majumdar, Rwitajit ; Sharma, Niti Nipun
Author_Institution :
Dept. of Mech. Eng., Birla Inst. of Technol. & Sci., Pilani, India
Volume :
11
Issue :
6
fYear :
2012
Firstpage :
1117
Lastpage :
1121
Abstract :
Nanoswimmers are important because of their potential use for the purpose of drug delivery, monitoring, and diagnostics for in vivo biomedical application. They mimic microorganisms and mostly modeled as propelled by beating or rotating flagella. In the vast literature available on modeling of flagellar propulsion, the flagellum is considered constant diameter where as the actual microorganism have tapered flagella. The present study deals with the modeling and simulation of planar wave propagation through a tapered flagellum of a nanoswimmer for a given taper ratio. The performance parameters of velocity and efficiency are compared with the uniform diameter case. Taper diameter modeling of flagellum gives a superior performance by indicating higher velocity and efficiency. The parametric study with respect to the elasticity of the material of the flagellum and its beat frequency is also analyzed. The performance increases with increasing frequency, and the maxima for both velocity and efficiency of the tapered case is reached at a lower elasticity than the uniform case. The maximum efficiency of the taper case is almost double the maxima of the uniform diameter flagellum. The observations in the present study can be utilized while designing artificial flagellum for nanoswimmers and suggests that the tapered flagellum would be a more optimal choice of design as compared to the uniform one of the same volume.
Keywords :
biomechanics; drug delivery systems; elasticity; microorganisms; nanobiotechnology; artificial flagellum; beat frequency; drug delivery; elasticity; flagellar propulsion modeling; in vivo biomedical application; microorganisms; planar wave propagation modeling; planar wave propagation simulation; taper case efficiency; taper diameter modeling; taper ratio; tapered flagellated nanoswimmer; uniform diameter flagellum; Drag; Elasticity; Force; Mathematical model; Microorganisms; Propulsion; Shape; Biological system modeling; elasticity; nanobioscience; propulsion;
fLanguage :
English
Journal_Title :
Nanotechnology, IEEE Transactions on
Publisher :
ieee
ISSN :
1536-125X
Type :
jour
DOI :
10.1109/TNANO.2012.2214230
Filename :
6275495
Link To Document :
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