First results from a YAP:Ce gamma camera for small animal studies

Author

De Notaristefani, F. ; Pani, R. ; Scopinaro, F. ; Barone, L.M. ; Blazek, K. ; De Vincentis, G. ; Malatesta, T. ; Maly, P. ; Pellegrini, R. ; Pergola, A. ; Soluri, A. ; Vittori, F.

Author_Institution

Dept. of Phys., Rome Univ., Italy

Volume

43

Issue

6

fYear

1996

fDate

12/1/1996 12:00:00 AM

Firstpage

3264

Lastpage

3271

Abstract

The YAP (yttrium aluminum perovskite) camera is a novel gamma camera with intrinsic submillimeter spatial resolution and detection efficiency comparable to a standard Anger camera. At the first stage, it is a miniature gamma camera with a field of view of 4×4 cm² and is currently utilized for radio tracer studies on small animals. The YAP camera consists of a multicrystal array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel hole collimator. The preliminary results are presented and discussed, in particular the intrinsic characteristics of the scintillating array, which are measured, as well as the position linearity and the spatial resolution, with a parallel collimator. Images were obtained from ^99mTc line source and nude Balb C mice, which have been injected with ^99mTc MDP, a bone-seeking agent. The observed images show the importance of the small-field YAP camera in radiopharmaceutical research

Keywords

biological techniques; biomedical equipment; cerium; gamma-ray detection; image resolution; photomultipliers; position sensitive particle detectors; positron emission tomography; single photon emission computed tomography; solid scintillation detectors; yttrium compounds; ^99mTc MDP; ^99mTc line source; Hamamatsu R2486; PET; SPECT; Tc; YAP:Ce; YAP:Ce gamma camera; YAlO3:Ce; bone-seeking agent; detection efficiency; field of view; intrinsic characteristics; intrinsic submillimeter spatial resolution; miniature gamma camera; multicrystal array; nude Balb C mice; parallel collimator; parallel hole collimator; position linearity; position sensitive photomultiplier tube; radio tracer studies; radiopharmaceutical research; scintillating array; small animal studies; spatial resolution; standard Anger camera; Aluminum; Animals; Cameras; Collimators; Gamma ray detection; Gamma ray detectors; Photomultipliers; Position measurement; Spatial resolution; Yttrium;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.552733

Filename

552733