DocumentCode :
128733
Title :
Dynamic MR-based respiratory motion compensation for hybrid PET/MR system
Author :
Shun Miao ; Rui Liao ; Moran, Guadalupe ; Butler, J. ; Li Pan ; Wang, Z. Jane
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of British Columbia, Vancouver, BC, Canada
fYear :
2014
fDate :
9-11 June 2014
Firstpage :
1915
Lastpage :
1920
Abstract :
This paper describes a novel respiratory motion compensation (MC) technique for hybrid PET/MR system. Existing PET/MR respiratory MC techniques mainly rely on respiratory gating to reconstruct 3D MR images for different respiratory phases, and use image registration techniques to estimate the deformation between different respiratory phases. A well known limitation of respiratory gating is its assumption that breathing motion is perfectly periodic, therefore MC techniques based on gated MR are sensitive to irregular breathing patterns. To address this limitation, the proposed technique uses dynamic 2D MRIs for PET/MR respiratory motion estimation. A static 3D MRI and a series of dynamic 2D MRIs are acquired before and during the PET data acquisition, respectively. The dynamic 2D MRIs are registered against the static 3D MRI using a novel deformable 2D+t to 3D image registration method to derive a 3D+t deformation field, which is then used for motion corrected PET reconstruction. The proposed method is validated on synthetic PET/MR data and real MR data, demonstrating its efficacy to compensate for irregular respiratory motion and to deblur the PET image.
Keywords :
biomedical MRI; data acquisition; image reconstruction; image registration; medical image processing; motion compensation; pneumodynamics; positron emission tomography; 3D image registration; 3D magnetic resonance image reconstruction; PET data acquisition; breathing motion; deformable 2D+t image registration; dynamic 2D MRI; dynamic magnetic resonance-based respiratory motion compensation; hybrid PET-MRI system; image registration; image registration techniques; irregular breathing patterns; respiratory gating; static 3D MRI; Dynamics; Image reconstruction; Logic gates; Magnetic resonance imaging; Positron emission tomography; Three-dimensional displays;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Industrial Electronics and Applications (ICIEA), 2014 IEEE 9th Conference on
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4799-4316-6
Type :
conf
DOI :
10.1109/ICIEA.2014.6931481
Filename :
6931481
Link To Document :
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