Title :
PET system calibration and attenuation correction
Author :
Pawitan, Y. ; Kohlmyer, S. ; Lewellen, T. ; O´Sullivan, F.
Author_Institution :
Dept. of Radiol., Washington Univ., Seattle, WA, USA
fDate :
6/1/1997 12:00:00 AM
Abstract :
A statistical model involving machine calibration factors in PET is developed based on the analysis of the correlation structure of the blank scan data. These factors include the nonuniform detector efficiencies and the geometric effects. The crystal interference effect is shown to be the main feature of the correlation function. A likelihood based theory is developed and the maximum likelihood estimates of the factors are derived. In the application of the model, estimated machine effects are used to calibrate the transmission scan and a robust smoothing is then applied to get the attenuation correction factor. The proposed technique is illustrated with studies on the GE Advance PET Scanner
Keywords :
biomedical equipment; calibration; correlation methods; gamma-ray absorption; gamma-ray detection; maximum likelihood estimation; positron emission tomography; smoothing methods; GE Advance PET Scanner; PET system calibration; attenuation correction; blank scan data; correlation structure; crystal interference effect; geometric effects; likelihood based theory; machine calibration factors; machine effects; maximum likelihood estimates; nonuniform detector efficiencies; robust smoothing; statistical model; torso phantom example; transmission scan; Attenuation; Calibration; Detectors; Educational institutions; Image reconstruction; Interference; Noise reduction; Positron emission tomography; Smoothing methods; Statistical analysis;
Journal_Title :
Nuclear Science, IEEE Transactions on
